Medicine
Bupivacaine and Epinephrine 250 mg/0.25 mg per 50 mL injection
Bupivacaine and Epinephrine 250 mg/0.25 mg per 50 mL injection is a generic prescription medicine for perineural use, made by 2 labelers, with its source record on the US FDA register. It is available on request for export supply from India to licensed hospitals, importers and physicians.
Availability
Export supply from India to licensed buyers
Typical lead time
On request
Counted from payment and complete documents
Shipping
Ambient
Store at 20 °C to 25 °C (68 °F to 77 °F), excursions permitted between 15 °C…
Key facts
- Active ingredient (INN)
- Bupivacaine and Epinephrine
- Brand
- Sold under the generic name
- Strength
- 250 mg/0.25 mg per 50 mL
- Dosage form
- Injection
- Route
- Perineural
- Packs
- 25 cartons of 50 mL, 50 mL, 1 vial of 50 mL and 1 more
- Manufacturers
- HealthFirstHospira
- Origin register
- US FDA, United States
- Storage
- Store at 20 °C to 25 °C (68 °F to 77 °F), excursions permitted between 15 °C to 30 °C (59 °F to 86 °F).
- Cold chain
- Not required on record
- Prescription status
- Prescription only
- Controlled substance
- Not recorded as controlled
- HS code (indicative)
- 3004.90Indicative only. Your customs broker confirms the final tariff code.
- Marketing category
- marketed
- Marketed since
- 26 July 2005
- Identifiers
- RxCUI 1012377, 1012384, 1012396 +7DailyMed set ID 02a845c3-4521-4926-e397-25ab536e7cf6, 99516811-56e2-9c8a-e053-2a95a90ac9cbNDC 0409-9046, 51662-1399Application ANDA071170, ANDA070968
Record updated 12 November 2026
Documents available
Documents that can be provided with this medicine. Your regulator may ask for more, and the quote lists the full set.
No document list is recorded for this medicine yet. Tell us which documents your regulator needs (for example a CoA, COPP or GMP certificate) when you request a quote.
Packs
Packs from every labeler of this generic presentation.
| Pack | Code | Labeler | Marketed since |
|---|---|---|---|
| 25 carton in 1 box / 1 vial, multi-dose in 1 carton / 50 mL in 1 vial, multi-dose | 0409-9046-01 | Hospira | 26 July 2005 |
| 50 mL in 1 vial, multi-dose | 51662-1399-1 | HealthFirst | 9 December 2019 |
| 1 vial, multi-dose in 1 pouch / 50 mL in 1 vial, multi-dose | 51662-1399-2 | HealthFirst | 26 January 2021 |
| 25 pouch in 1 case / 1 vial, multi-dose in 1 pouch / 50 mL in 1 vial, multi-dose | 51662-1399-3 | HealthFirst | 26 January 2021 |
Status by register
Where this medicine is registered, from the source record and the regulator data we hold. Ask us about a country that is not listed.
| Register | Status | Source |
|---|---|---|
| US FDA | Listed, marketed | Source record for this pageChecked 12 November 2026 |
| US FDA | First approved 3 October 1972 | Drugs@FDA |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Import route
Pick the destination country to see the legal import route, who applies and typical timelines, from our import guide for that country.
Import guides are available for 25 countries. Pick one to see its route summary.
BrazilColombiaEgyptEthiopiaGhanaIraqKazakhstanKenyaAll import guides
Alternatives
Other makers and brands of Bupivacaine and Epinephrine 250 mg/0.25 mg per 50 mL injection.
Other strengths and forms of Bupivacaine and Epinephrine
Clinical summary
Bupivacaine and Epinephrine is a fixed-dose combination of an amide local anesthetic, a catecholamine and an alpha-adrenergic agonist. It is available as injection for perineural, epidural and intracaudal use. MedsAcross supplies Bupivacaine and Epinephrine for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
Read about Bupivacaine and EpinephrineFor healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
Data sources
- DailyMed label record · Checked 12 November 2026
- Marcaine prescribing information (Hospira) · U.S. National Library of Medicine, DailyMed
Need Bupivacaine and Epinephrine 250 mg/0.25 mg per 50 mL injection for your hospital or patient?
Send one request with the destination country and quantity. We confirm availability, lead time and the documents your regulator needs.