Molecule

Cefazolin

Also known as cefazolin sodium

Available on requestCold chainAntibiotics

Presentations: 22
Brands: 0
Manufacturers: 0
Available from stock: 0

Cefazolin is a cephalosporin antibacterial indicated for treatment of infections caused by susceptible isolates of the designated microorganisms in adult and pediatric patients for whom appropriate dosing with this formulation can be achieved, among other approved uses. MedsAcross supplies Cefazolin for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.

Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review

Key facts

Pharmacological class: Cephalosporin Antibacterial
ATC classification: J01DB04 Cefazolin · Cephalosporin antibiotic
US FDA first approval: 4 October 1973
EU status: Not recorded
Orphan designation: Not recorded
WHO essential medicine: Not recorded
India (CDSCO): Not yet confirmed against CDSCO approval lists
Routes: Intravenous, Intramuscular, Parenteral
Dosage forms: Powder for injection, Injection
Identifiers: UNII IHS69L0Y4TRxCUI 2180CAS 25953-19-9DrugBank DB01327Q415739

Clinical information

From the regulator-approved product information. Each section names its source.

Uses

Cefazolin for Injection and Dextrose Injection is a cephalosporin antibacterial indicated for: Treatment of the following infections caused by susceptible isolates of the designated microorganisms in adult and pediatric patients for whom appropriate dosing with this formulation can be achieved: Respiratory tract infections. Urinary tract infections. Skin and skin structure infections. Biliary tract infections. Bone and joint infections. Genital infections. Septicemia. Endocarditis. Perioperative prophylaxis in adults and pediatric patients aged 10 to 17 years old for whom appropriate dosing with this formulation can be achieved.

Source: US FDA prescribing information

How it works

Cefazolin is an antibacterial drug.

Source: US FDA prescribing information

Dosing overview

If a dose of Cefazolin for Injection and Dextrose Injection is required that does not equal 1 gram, 2 grams or 3 grams, this product is not recommended for use and an alternative formulation of cefazolin should be considered. For intravenous use only administered over approximately 30 minutes.

Source: US FDA prescribing information

Contraindications

Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams Hypersensitivity to Cefazolin or the Cephalosporin Class of Antibacterial Drugs, Penicillins, or Other Beta-lactams Cefazolin for Injection and Dextrose Injection is contraindicated in patients who have a history of immediate hypersensitivity reactions (e.g., anaphylaxis, serious skin reactions) to cefazolin or the cephalosporin class of antibacterial drugs, penicillins, or other beta-lactams.

Source: US FDA prescribing information

Warnings and precautions

Hypersensitivity reactions: Cross-hypersensitivity may occur in up to 10% of patients with a history of penicillin allergy. If an allergic reaction occurs, discontinue the drug. Clostridioides difficile -associated Diarrhea (CDAD): May range from mild diarrhea to fatal colitis. Evaluate if diarrhea occurs. Prothrombin Activity: May be associated with a fall in prothrombin activity. Prothrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicated

Source: US FDA prescribing information

Side effects

The following serious adverse reactions to Cefazolin for Injection and Dextrose Injection are described below and elsewhere in the labeling: Hypersensitivity Reactions to Cefazolin, Cephalosporins, Penicillins, or Other Beta-lactams Seizures in Patients with Renal Impairment Clostridioides difficile -associated Diarrhea Prothrombin Activity Adult and Pediatric Patients: Most common adverse reactions: gastrointestinal (nausea, vomiting, diarrhea), and allergic reactions (anaphylaxis, urticaria, skin rash). Pediatric Patients with Perioperative Prophylaxis: The most frequently reported adverse reactions (incidence ≥ 5%) were nausea, infusion site pain, and headache.

Source: US FDA prescribing information

Interactions

The renal excretion of cefazolin is inhibited by probenecid. Co-administration of probenecid with Cefazolin for Injection and Dextrose Injection is not recommended. Probenecid: The renal excretion of cefazolin is inhibited by probenecid. Co-administration of probenecid with cefazolin for injection is not recommended.

Source: US FDA prescribing information

Storage

Store the unactivated unit at 20-25°C (68-77°F). Excursions permitted to 15-30°C (59-86°F). Do not freeze. As with other cephalosporins, reconstituted Cefazolin for Injection USP and Dextrose Injection USP tends to darken depending on storage conditions, within the stated recommendations.

Source: US FDA prescribing information

For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.

All presentations

22 presentations of Cefazolin, sorted by availability.

Medicine	Manufacturer	Register	Availability
Cefazolin 1 g powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 10 g powder for injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 330 mg/mL powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 2 g powder for injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 1 g/50 mL injectionIntravenous Cold chainGeneric name	—	US FDA	Available on request
Cefazolin 3 g powder for injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 1 g powder for injectionIntramuscular, intravenous, parenteralGeneric name	—	US FDA	Available on request
Cefazolin 1 g/3 mL powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 10 g powder for injectionIntravenous, parenteralGeneric name	—	US FDA	Available on request
Cefazolin 100 g powder for injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 2 g powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 2 g/100 mL injectionIntravenous Cold chainGeneric name	—	US FDA	Available on request
Cefazolin 2 g/50 mL injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 20 g powder for injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 225 mg/mL powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 3 g powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 3 g/150 mL injectionIntravenous Cold chainGeneric name	—	US FDA	Available on request
Cefazolin 3 g/50 mL injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 300 g powder for injectionIntravenousGeneric name	—	US FDA	Available on request
Cefazolin 500 mg powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 500 mg/2.2 mL powder for injectionIntramuscular, intravenousGeneric name	—	US FDA	Available on request
Cefazolin 500 mg powder for injectionIntramuscular, intravenous, parenteralGeneric name	—	US FDA	Available on request

Regulatory status

Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.

Register	Status	Source
US FDA	First approved 4 October 1973	Drugs@FDA
EU (EMA)	Not recorded	—
India (CDSCO)	Not yet confirmed against CDSCO approval lists	—
United States	Registered	US FDA (NDC directory, openFDA)Checked 12 November 2026

Conditions

Conditions linked to Cefazolin in public data. This is not a list of approved uses, see the clinical information.

Bacterial pneumonia Escherichia coli infectious disease Gram-negative bacterial infection Infective endocarditis Pseudomonas septicemia Staphylococcal infection Upper respiratory tract infection Urinary tract infection

Questions and answers

Is Cefazolin available for export from India?

Yes, on request. MedsAcross lists 22 presentations of Cefazolin and sources them for licensed hospitals, importers and physicians against valid import documents.

Is Cefazolin approved by the US FDA?

Yes. The US FDA first approved Cefazolin on 4 October 1973, according to Drugs@FDA.

Does Cefazolin need cold chain shipping?

At least one listed presentation of Cefazolin must be kept cold, so it is shipped in temperature-controlled packaging. Check the storage line on each presentation.

Which ATC class is Cefazolin in?

Cefazolin is classified under ATC code J01DB04 (Cefazolin).

References

Cefazolin Sodium prescribing information (B. Braun Medical). U.S. National Library of Medicine, DailyMed. Retrieved 10 March 2025

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