Uses
ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is an anticoagulant for blood collection for use only with apheresis devices.
Source: US FDA prescribing information
Fixed-dose combination
Citric acid, Dextrose and Trisodium
Also known as citric acid monohydrate, dextrose monohydrate, trisodium citrate dihydrate
Available on request
- Presentations
- 1
- Brands
- 1
- Manufacturers
- 1
- Available from stock
- 0
Citric acid, Dextrose and Trisodium is a fixed-dose combination of an anti-coagulant and a calculi dissolution agent. It is available as injection for intravenous use. MedsAcross supplies Citric acid, Dextrose and Trisodium for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
Key facts
- Pharmacological class
- Anti-coagulant, Calculi Dissolution Agent, Acidifying Activity, Calcium Chelating Activity, Decreased Coagulation Factor Activity
- US FDA first approval
- Not recorded
- EU status
- Not recorded
- Orphan designation
- Not recorded
- WHO essential medicine
- Not recorded
- India (CDSCO)
- Not yet confirmed against CDSCO approval lists
- Routes
- Intravenous
- Dosage forms
- Injection
- Fixed-dose combination of
- Citric acid, Dextrose, Trisodium
Clinical information
From the regulator-approved product information. Each section names its source.
How it works
ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A acts as an extracorporeal anticoagulant by binding the free calcium in the blood. Calcium is a necessary co-factor to several steps in the clotting cascade. The following ingredients are key components of the solution: Citric acid for pH regulation Sodium Citrate anticoagulates Dextrose for isotonicity This solution has no pharmacological effect.
Source: US FDA prescribing information
Dosing overview
ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is added to tubing sets during apheresis procedures. ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A may only be used with apheresis devices. For instructions on the use of the solution see the apheresis device operator's manual. Follow the directions for connecting the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A bag to the apheresis system.
Source: US FDA prescribing information
Contraindications
DO NOT INFUSE ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A DIRECTLY TO THE PATIENTS.
Source: US FDA prescribing information
Warnings and precautions
Verify that the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A has been securely attached to the Anticoagulant (AC) line on the system tubing set. Use aseptic technique throughout all procedures to ensure donor safety and quality. Do not reuse. Discard unused or partially used solution bags.
Source: US FDA prescribing information
Side effects
Citrate reactions or toxicity may occur with the infusion and return of blood containing citrate anticoagulant. The recipient of the blood containing citrate should be monitored for the signs and symptoms of citrate toxicity. The signs and symptoms of citrate toxicity begin with paresthesia, a "tingling" sensation around the mouth or in the extremities, followed by severe reactions that are characterized by hypotension and possible cardiac arrhythmia. Citrate toxicity may occur more frequently in patients who are hypothermic, have impaired liver or renal function, or have low calcium levels because of an underlying disease.
Source: US FDA prescribing information
Storage
Store up to 25 °C. Protect from freezing.
Source: US FDA prescribing information
For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
All presentations
1 presentations of Citric acid, Dextrose and Trisodium, sorted by availability.
| Medicine | Active ingredient | Manufacturer | Register | Availability |
|---|---|---|---|---|
| Acd A 6 g/18.375 g/16.5 g per 750 mL injectionIntravenous | Citric acid, Dextrose and Trisodium | Terumo BCT | US FDA | Available on request |
Brands by market
1 brand names across 1 markets.
United States
Manufacturers
Regulatory status
Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.
| Register | Status | Source |
|---|---|---|
| US FDA | Not recorded | — |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Questions and answers
Is Citric acid, Dextrose and Trisodium available for export from India?
Yes, on request. MedsAcross lists 1 presentations of Citric acid, Dextrose and Trisodium and sources them for licensed hospitals, importers and physicians against valid import documents.
What brand names does Citric acid, Dextrose and Trisodium have?
The catalogue lists 1 brand names for Citric acid, Dextrose and Trisodium, including Acd A.
Does Citric acid, Dextrose and Trisodium need cold chain shipping?
No listed presentation of Citric acid, Dextrose and Trisodium is recorded as needing a cold chain. Storage conditions are shown on each presentation page.
References
- ACD A prescribing information (Terumo BCT). U.S. National Library of Medicine, DailyMed. Retrieved 15 June 2026
Request Citric acid, Dextrose and Trisodium for export supply
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