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Molecule

Desflurane

General Anesthetic
Available on requestPain and anaesthesia
Presentations
2
Brands
1
Manufacturers
1
Available from stock
0

Desflurane is a general anesthetic indicated for induction and/or maintenance of anesthesia in adults, among other approved uses. It is available as inhalation solution. MedsAcross supplies Desflurane for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.

Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review

Key facts

Pharmacological class
General Anesthetic, General Anesthesia
ATC classification
N01AB07 Desflurane · Anaesthetics, subgroup N01A, subgroup N01AB
US FDA first approval
18 September 1992
EU status
Not recorded
Orphan designation
Not recorded
WHO essential medicine
Not recorded
India (CDSCO)
Not yet confirmed against CDSCO approval lists
Routes
Inhalation
Dosage forms
Inhalation solution
Identifiers
UNII CRS35BZ94QRxCUI 27340CAS 57041-67-5DrugBank DB01189Q419383

Clinical information

From the regulator-approved product information. Each section names its source.

Uses

SUPRANE, a general anesthetic, is an inhalation agent indicated: • for induction and/or maintenance of anesthesia in adults. • for maintenance of anesthesia in pediatric patients following induction with agents other than SUPRANE and intubation.

Source: US FDA prescribing information

Dosing overview

Only persons trained in the administration of general anesthesia should administer SUPRANE. Only a vaporizer specifically designed and designated for use with desflurane should be utilized for its administration. Facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available. SUPRANE is administered by inhalation. The administration of general anesthesia must be individualized based on the patient’s response. Hypotension and respiratory depression increase as anesthesia with SUPRANE is deepened. The minimum alveolar concentration (MAC) of SUPRANE decreases with increasing patient age. The MAC for SUPRANE is also reduced by concomitant N 2 O administration. The dose should be adjusted accordingly.

Source: US FDA prescribing information

Contraindications

The use of SUPRANE is contraindicated in the following conditions: • Known or suspected genetic susceptibility to malignant hyperthermia. • Patients in whom general anesthesia is contraindicated. • Induction of anesthesia in pediatric patients. • Patients with known sensitivity to SUPRANE or to other halogenated agents. • Patients with a history of moderate to severe hepatic dysfunction following anesthesia with SUPRANE or other halogenated agents and not otherwise explained. • Patients with known or suspected genetic susceptibility to malignant hyperthermia. • Patients in whom general anesthesia is contraindicated. • Induction of anesthesia in pediatric patients.

Source: US FDA prescribing information

Warnings and precautions

• Malignant Hyperthermia: Malignant hyperthermia may occur, especially in individuals with known or suspected susceptibility based on genetic factors or family history. Discontinue triggering agents, administer intravenous dantrolene sodium, and apply supportive therapies. • Perioperative Hyperkalemia: Perioperative hyperkalemia may occur. Patients with latent or overt neuromuscular disease, particularly with Duchenne muscular dystrophy, appear to be most vulnerable. Early, aggressive intervention is recommended. • Respiratory Adverse Reactions in Pediatric Patients: - Not approved for maintenance of anesthesia in non-intubated children due to an increased incidence of respiratory adverse reactions. Monitor and treat accordingly. - May cause airway narrowing and increased airway resistance in children with asthma or a history of recent upper airway infection.

Source: US FDA prescribing information

Side effects

Most common adverse reactions (incidence> 10%) are coughing, breath holding, apnea, nausea, vomiting.

Source: US FDA prescribing information

Interactions

No clinically significant adverse interactions with commonly used preanesthetic drugs, or drugs used during anesthesia (muscle relaxants, intravenous agents, and local anesthetic agents) were reported in clinical trials. The effect of SUPRANE on the disposition of other drugs has not been determined. Similar to isoflurane, SUPRANE does not predispose to premature ventricular arrhythmias in the presence of exogenously infused epinephrine in swine. • Concomitant use of N 2 O, benzodiazepines and/or opioids reduces the MAC of SUPRANE. Adjust dose accordingly. • SUPRANE decreases the doses of neuromuscular blocking agents required. Adjust dose accordingly.

Source: US FDA prescribing information

For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.

All presentations

2 presentations of Desflurane, sorted by availability.

MedicineManufacturerRegisterAvailability
Suprane 240 mL/240 mL inhalation solutionInhalationBaxter HealthcareUS FDAAvailable on request
Desflurane 240 mL/240 mL inhalation solutionInhalationGeneric name—US FDAAvailable on request

Brands by market

1 brand names across 1 markets.

Brand names by country

United States

Manufacturers

Regulatory status

Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.

RegisterStatusSource
US FDAFirst approved 18 September 1992Drugs@FDA
EU (EMA)Not recorded—
India (CDSCO)Not yet confirmed against CDSCO approval lists—
United StatesRegisteredUS FDA (NDC directory, openFDA)Checked 12 November 2026

Conditions

Conditions linked to Desflurane in public data. This is not a list of approved uses, see the clinical information.

Questions and answers

Is Desflurane available for export from India?

Yes, on request. MedsAcross lists 2 presentations of Desflurane and sources them for licensed hospitals, importers and physicians against valid import documents.

What brand names does Desflurane have?

The catalogue lists 1 brand names for Desflurane, including Suprane.

Is Desflurane approved by the US FDA?

Yes. The US FDA first approved Desflurane on 18 September 1992, according to Drugs@FDA.

Does Desflurane need cold chain shipping?

No listed presentation of Desflurane is recorded as needing a cold chain. Storage conditions are shown on each presentation page.

Which ATC class is Desflurane in?

Desflurane is classified under ATC code N01AB07 (Desflurane).

References

  1. SUPRANE prescribing information (Baxter Healthcare). U.S. National Library of Medicine, DailyMed. Retrieved 14 October 2025

Request Desflurane for export supply

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