Dimethyl sulfoxide is a prescription medicine indicated for the symptomatic relief of patients with interstitial cystitis. It is available as irrigation solution for intravesical use. MedsAcross supplies Dimethyl sulfoxide for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
From the regulator-approved product information. Each section names its source.
RIMSO-50 ® (dimethyl sulfoxide) is indicated for the symptomatic relief of patients with interstitial cystitis. RIMSO-50 ® has not been approved as being safe and effective for any other indication. There is no clinical evidence of effectiveness of dimethyl sulfoxide in the treatment of bacterial infections of the urinary tract.
Source: US FDA prescribing information
Instillation of 50 mL of RIMSO-50 ® (dimethyl sulfoxide) directly into the bladder may be accomplished by catheter or asepto syringe and allow to remain for 15 minutes. Application of an analgesic lubricant gel such as lidocaine jelly to the urethra is suggested prior to insertion of the catheter to avoid spasm. The medication is expelled by spontaneous voiding. It is recommended that the treatment be repeated every two weeks until maximum symptomatic relief is obtained. Thereafter, time intervals between therapy may be increased appropriately. Administration of oral analgesic medication or suppositories containing belladonna and opium prior to the instillation of RIMSO-50 ® can reduce bladder spasm.
Source: US FDA prescribing information
None known.
Source: US FDA prescribing information
Dimethyl sulfoxide can initiate the liberation of histamine and there has been occasional hypersensitivity reaction with topical administration of dimethyl sulfoxide. This hypersensitivity has been reported in one patients receiving intravesical RIMSO-50 ®. The physician should be cognizant of this possibility in prescribing RIMSO-50 ®. If anaphylactoid symptoms develop, appropriate therapy should be instituted.
Source: US FDA prescribing information
A garlic-like taste may be noted by the patient within a few minutes after instillation of RIMSO-50 ® (dimethyl sulfoxide). This taste may last several hours and because of the presence of metabolites, an odor on the breath and skin may remain for 72 hours. Transient chemical cystitis has been noted following instillation of dimethyl sulfoxide. The patient may experience moderately severe discomfort on administration. Usually this becomes less prominent with repeated administration.
Source: US FDA prescribing information
Store at 20° to 25°C (68° to 77°F). Protect from strong light.
Source: US FDA prescribing information
For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
2 presentations of Dimethyl sulfoxide, sorted by availability.
| Medicine | Manufacturer | Register | Availability |
|---|---|---|---|
| Dimethyl sulfoxide 0.54 g/mL irrigation solutionIntravesicalGeneric name | — | US FDA | Available on request |
| Rimso-50 0.54 g/mL irrigation solutionIntravesical | Mylan Institutional | US FDA | Available on request |
1 brand names across 1 markets.
United States
Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.
| Register | Status | Source |
|---|---|---|
| US FDA | First approved 4 April 1978 | Drugs@FDA |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Yes, on request. MedsAcross lists 2 presentations of Dimethyl sulfoxide and sources them for licensed hospitals, importers and physicians against valid import documents.
The catalogue lists 1 brand names for Dimethyl sulfoxide, including Rimso-50.
Yes. The US FDA first approved Dimethyl sulfoxide on 4 April 1978, according to Drugs@FDA.
No listed presentation of Dimethyl sulfoxide is recorded as needing a cold chain. Storage conditions are shown on each presentation page.
Dimethyl sulfoxide is classified under ATC code G04BX13 (Dimethyl sulfoxide).
Tell us the strength, quantity and destination country. Our team replies with availability, lead time and the import documents needed.