Skip to content
MedsAcross

Molecule

Dopamine

Also known as dopamine hydrochloride
Available on requestCardiology
Presentations
9
Brands
0
Manufacturers
0
Available from stock
0

Dopamine is a catecholamine indicated to improve hemodynamic status in patients in distributive shock or shock due to reduced cardiac output. It is available as injection for intravenous use. MedsAcross supplies Dopamine for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.

Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review

Key facts

Pharmacological class
Catecholamine
ATC classification
C01CA04 Dopamine · Butyroxan
US FDA first approval
25 February 1974
EU status
Authorised
Orphan designation
No
WHO essential medicine
Not recorded
India (CDSCO)
Not yet confirmed against CDSCO approval lists
Routes
Intravenous
Dosage forms
Injection
Identifiers
UNII VTD58H1Z2XRxCUI 3628CAS 51-61-6DrugBank DB00988Q170304

Clinical information

From the regulator-approved product information. Each section names its source.

Uses

Dopamine HCl Injection is indicated to improve hemodynamic status in patients in distributive shock or shock due to reduced cardiac output. Dopamine HCl Injection is a catecholamine indicated to improve hemodynamic status in patients in shock.

Source: US FDA prescribing information

How it works

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4 dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine elicits its pharmacological action by activating dopamine D1 and D2 receptors, beta 1 receptors and alpha 1 receptors. The activation of different receptors leading to its effects are dependent on dopamine dose.

Source: US FDA prescribing information

Dosing overview

Correct hypovolemia, acidosis, and hypoxia prior to use. Administer in a large vein with an infusion pump preferably in an intensive care setting. Recommended starting dosage in adults and pediatric patients is 2 to 5 mcg/kg/minute as a continuous intravenous infusion. Titrate in 5 to 10 mcg/kg/minute increments based on hemodynamic response and tolerability, up to not more than 50 mcg/kg/minute. See the Full Prescribing Information for important preparation instructions and drug incompatibilities.

Source: US FDA prescribing information

Warnings and precautions

• Tissue ischemia: Severe peripheral and visceral vasoconstriction can occur. Address hypovolemia prior to use, monitor extremities, and infuse into large vein. • Cardiac arrhythmias: Monitor closely. • Hypotension after abrupt discontinuation: Gradually reduce infusion rate while expanding blood volume with intravenous fluids. • Severe hypersensitivity reactions due to sodium metabisulfite excipient: May cause anaphylaxis including life‑threatening or less severe asthmatic episodes in susceptible individuals.

Source: US FDA prescribing information

Side effects

The following adverse reactions are described elsewhere in the labeling: • Tissue Ischemia • Cardiac Arrhythmias • Hypotension • Severe Hypersensitivity Reactions The following adverse reactions have been identified during postapproval use of dopamine. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Cardiac Disorders: anginal pain, palpitation Gastrointestinal Disorders: nausea, vomiting Metabolism and Nutrition Disorders: azotemia Nervous System Disorders: headache, anxiety Respiratory Disorders: dyspnea Skin and Subcutaneous Tissue Disorders: piloerection Vascular Disorders: hypertension The most common adverse reaction is localized vasoconstriction due to extravasation.

Source: US FDA prescribing information

Interactions

See Table 1 for clinically significant drug interactions with dopamine. Table 1: Clinically Significant Drug Interactions with Dopamine Halogenated Anesthetics Clinical Impact: Concomitant use may increase cardiac autonomic irritability and can sensitize the myocardium to the action of dopamine which may lead to ventricular arrhythmias and hypertension. Intervention: Monitor cardiac rhythm. Examples: desflurane, enflurane, isoflurane, and sevoflurane. MAO Inhibitors Clinical Impact: Because dopamine is metabolized by monoamine oxidase (MAO), inhibition of this enzyme prolongs and potentiates the effect of dopamine which may result in severe hypertension and cardiac arrhythmia.

Source: US FDA prescribing information

For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.

All presentations

9 presentations of Dopamine, sorted by availability.

MedicineManufacturerRegisterAvailability
Dopamine 200 mg/5 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 400 mg/10 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 400 mg/250 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 800 mg/250 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 800 mg/500 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 200 mg/250 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 400 mg/5 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 400 mg/500 mL injectionIntravenousGeneric name—US FDAAvailable on request
Dopamine 800 mg/10 mL injectionIntravenousGeneric name—US FDAAvailable on request

Regulatory status

Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.

RegisterStatusSource
US FDAFirst approved 25 February 1974Drugs@FDA
EU (EMA)AuthorisedEMA medicines data
India (CDSCO)Not yet confirmed against CDSCO approval lists—
AustriaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
BelgiumRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
BulgariaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
CroatiaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
CyprusRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
CzechiaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
DenmarkRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
EstoniaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
FinlandRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
FranceRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
GermanyRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
GreeceRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
HungaryRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
IcelandRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
IrelandRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
ItalyRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
LatviaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
LiechtensteinRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
LithuaniaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
LuxembourgRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
MaltaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
NetherlandsRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
NorwayRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
PolandRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
PortugalRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
RomaniaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
SlovakiaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
SloveniaRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
SpainRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
SwedenRegisteredEuropean Medicines Agency (central authorisation)Checked 12 November 2026
United StatesRegisteredUS FDA (NDC directory, openFDA)Checked 12 November 2026

Conditions

Conditions linked to Dopamine in public data. This is not a list of approved uses, see the clinical information.

Questions and answers

Is Dopamine available for export from India?

Yes, on request. MedsAcross lists 9 presentations of Dopamine and sources them for licensed hospitals, importers and physicians against valid import documents.

Is Dopamine approved by the US FDA?

Yes. The US FDA first approved Dopamine on 25 February 1974, according to Drugs@FDA.

Is Dopamine authorised in the European Union?

Yes. Dopamine has a central EU marketing authorisation (status: authorised), according to European Medicines Agency data.

Does Dopamine need cold chain shipping?

No listed presentation of Dopamine is recorded as needing a cold chain. Storage conditions are shown on each presentation page.

Which ATC class is Dopamine in?

Dopamine is classified under ATC code C01CA04 (Dopamine).

References

  1. DOPamine Hydrochloride prescribing information (Hospira). U.S. National Library of Medicine, DailyMed. Retrieved 13 May 2026
  2. Neoatricon: European public assessment report (EPAR). European Medicines Agency. Retrieved 4 July 2025

Request Dopamine for export supply

Tell us the strength, quantity and destination country. Our team replies with availability, lead time and the import documents needed.