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Molecule

Ferric ferrocyanide

Decorporation Agent
Available on requestAntidotes
Presentations
1
Brands
1
Manufacturers
1
Available from stock
0

Ferric ferrocyanide is a decorporation agent indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium, in order to increase their rates of elimination. MedsAcross supplies Ferric ferrocyanide for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.

Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review

Key facts

Pharmacological class
Decorporation Agent, Chelating Activity, Ion Exchange Activity
ATC classification
V03AB31 Ferric ferrocyanide · Antidote
US FDA first approval
Not recorded
EU status
Not recorded
Orphan designation
Not recorded
WHO essential medicine
Not recorded
India (CDSCO)
Not yet confirmed against CDSCO approval lists
Routes
Oral
Dosage forms
Capsule
Identifiers
UNII TLE294X33ARxCUI 24902CAS 14038-43-8DrugBank DB06783Q421894

Clinical information

From the regulator-approved product information. Each section names its source.

Uses

Radiogardase is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium, in order to increase their rates of elimination. Radiogardase is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Source: US FDA prescribing information

How it works

Prussian blue insoluble, ferric hexacyanoferrate(II), acts by ion-exchange, adsorption, and mechanical trapping within the crystal structure, and has a high affinity for radioactive and non-radioactive cesium and thallium. Prussian blue insoluble binds cesium and thallium isotopes in the gastrointestinal tract after these isotopes are ingested or excreted in the bile by the liver, thereby reducing gastrointestinal reabsorption (enterohepatic circulation). The rate of cesium and thallium elimination is proportional to the duration and dose of prussian blue insoluble.

Source: US FDA prescribing information

Dosing overview

Adults and Adolescents: 3 grams orally three times a day. Pediatrics (2 – 12 years): 1 gram orally three times a day. Administer as soon as possible after internal contamination with cesium or thallium is suspected

Source: US FDA prescribing information

Warnings and precautions

Increased radiation absorbed dose to gastrointestinal mucosa: Monitor for decreased gastrointestinal motility. Constipation: Monitor and treat. Electrolyte abnormalities: Monitor serum electrolytes during treatment. Blue discoloration of stool, oral mucosa and dentition

Source: US FDA prescribing information

Side effects

Constipation was reported in 10 (24%) of 42 patients treated with Radiogardase. Severity of constipation was mild in 7 patients and moderate in 3 patients. Most common adverse reaction (incidence >24%) was constipation

Source: US FDA prescribing information

Interactions

Based on animal data, co-administration of Radiogardase with other decorporation agents does not affect the efficacy of Radiogardase for treatment of internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium.

Source: US FDA prescribing information

Storage

Storage Store at 20 °C to 25 °C (68 °F to 77 °F), excursions permitted between 15 °C and 30°C (between 59 °F and 86 °F). Brief exposure to temperatures up to 40 °C (104 °F) may be tolerated, provided the mean kinetic temperature does not exceed 25 °C (77 °F), however, minimize such exposure.

Source: US FDA prescribing information

For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.

All presentations

1 presentations of Ferric ferrocyanide, sorted by availability.

MedicineManufacturerRegisterAvailability
Radiogardase 500 mg capsuleOralHeyl Chem.-pharm. FabrikUS FDAAvailable on request

Brands by market

1 brand names across 1 markets.

Brand names by country

United States

Manufacturers

Regulatory status

Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.

RegisterStatusSource
US FDANot recorded—
EU (EMA)Not recorded—
India (CDSCO)Not yet confirmed against CDSCO approval lists—
United StatesRegisteredUS FDA (NDC directory, openFDA)Checked 12 November 2026

Conditions

Conditions linked to Ferric ferrocyanide in public data. This is not a list of approved uses, see the clinical information.

Questions and answers

Is Ferric ferrocyanide available for export from India?

Yes, on request. MedsAcross lists 1 presentations of Ferric ferrocyanide and sources them for licensed hospitals, importers and physicians against valid import documents.

What brand names does Ferric ferrocyanide have?

The catalogue lists 1 brand names for Ferric ferrocyanide, including Radiogardase.

Does Ferric ferrocyanide need cold chain shipping?

No listed presentation of Ferric ferrocyanide is recorded as needing a cold chain. Storage conditions are shown on each presentation page.

Which ATC class is Ferric ferrocyanide in?

Ferric ferrocyanide is classified under ATC code V03AB31 (Ferric ferrocyanide).

References

  1. Radiogardase prescribing information (Heyl Chem.-pharm. Fabrik). U.S. National Library of Medicine, DailyMed. Retrieved 7 October 2021

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