Glutamine is an amino acid indicated to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older. It is available as powder for oral solution. MedsAcross supplies Glutamine for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
From the regulator-approved product information. Each section names its source.
Endari is indicated to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older. ENDARI is an amino acid indicated to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older.
Source: US FDA prescribing information
The mechanism of action of the amino acid L-glutamine in treating sickle cell disease (SCD) is not fully understood. Oxidative stress phenomena are involved in the pathophysiology of SCD. Sickle red blood cells (RBCs) are more susceptible to oxidative damage than normal RBCs, which may contribute to the chronic hemolysis and vaso-occlusive events associated with SCD. The pyridine nucleotides, NAD + and its reduced form NADH, play roles in regulating and preventing oxidative damage in RBCs. L-glutamine may improve the NAD redox potential in sickle RBCs through increasing the availability of reduced glutathione.
Source: US FDA prescribing information
5 grams to 15 grams orally, twice daily based on body weight. Each dose of Endari should be mixed in 8 oz. (240 mL) of cold or room temperature beverage or 4 oz. to 6 oz. of food before ingestion.
Source: US FDA prescribing information
None None
Source: US FDA prescribing information
Most common adverse reactions (incidence > 10%) are constipation, nausea, headache, abdominal pain, cough, pain in extremity, back pain, and chest pain.
Source: US FDA prescribing information
No drug interaction studies have been conducted.
Source: US FDA prescribing information
Store at 20°C to 25°C (68°F to 77°F) away from direct sunlight.
Source: US FDA prescribing information
For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
2 presentations of Glutamine, sorted by availability.
| Medicine | Manufacturer | Register | Availability |
|---|---|---|---|
| Glutamine 5 g powder for oral solutionOralGeneric name | — | US FDA | Available on request |
| Endari 5 g powder for oral solutionOral | Emmaus Medical | US FDA | Available on request |
1 brand names across 1 markets.
United States
Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.
| Register | Status | Source |
|---|---|---|
| US FDA | Not recorded | — |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Conditions linked to Glutamine in public data. This is not a list of approved uses, see the clinical information.
Yes, on request. MedsAcross lists 2 presentations of Glutamine and sources them for licensed hospitals, importers and physicians against valid import documents.
The catalogue lists 1 brand names for Glutamine, including Endari.
No listed presentation of Glutamine is recorded as needing a cold chain. Storage conditions are shown on each presentation page.
Glutamine is classified under ATC code A16AA03 (Glutamine).
Tell us the strength, quantity and destination country. Our team replies with availability, lead time and the import documents needed.