Uses
MEGATOPE is indicated in adults for use in determinations of total blood and plasma volumes.
Source: US FDA prescribing information
Molecule
Human serum albumin i-131
Radiopharmaceutical Activity
Available on requestBiologicCold chain
- Presentations
- 2
- Brands
- 2
- Manufacturers
- 1
- Available from stock
- 0
Human serum albumin i-131 is a prescription medicine indicated in adults for use in determinations of total blood and plasma volumes. It is available as injection for intravenous use. MedsAcross supplies Human serum albumin i-131 for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
Key facts
- Pharmacological class
- Radiopharmaceutical Activity
- US FDA first approval
- Not recorded
- EU status
- Not recorded
- Orphan designation
- Not recorded
- WHO essential medicine
- Not recorded
- India (CDSCO)
- Not yet confirmed against CDSCO approval lists
- Routes
- Intravenous
- Dosage forms
- Injection
- Biologic
- Yes
- Identifiers
- UNII ACH35131L1RxCUI 314301Q27273861
Clinical information
From the regulator-approved product information. Each section names its source.
Dosing overview
Premedication Administer 10 drops of Strong Iodine Solution, USP (e.g., Lugol’s Solution) three times daily, beginning at least 24 hours before administration of MEGATOPE and continue for 1 week or 2 weeks thereafter to minimize the uptake of iodine-131. Recommended Dosage The recommended dose of MEGATOPE for total blood or plasma volume determination in adult patients is from 0.185 MBq to
Source: US FDA prescribing information
Contraindications
None Known.
Source: US FDA prescribing information
Warnings and precautions
Aseptic meningitis and pyrogenic reactions have been reported following cisternography with MEGATOPE. The safety and effectiveness of MEGATOPE for cisternography have not been established. MEGATOPE is not approved for this use.
Source: US FDA prescribing information
Side effects
The following adverse reactions have been identified with the use of radioiodinated albumin products. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Immune System Disorders: Hypersensitivity
Source: US FDA prescribing information
Storage
Store refrigerated at 2º to 8ºC (36° to 46°F) in suitable lead shield.
Source: US FDA prescribing information
For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
All presentations
2 presentations of Human serum albumin i-131, sorted by availability.
| Medicine | Manufacturer | Register | Availability |
|---|---|---|---|
| Megatope 1 mCi/mL injectionIntravenous Cold chain | Iso-Tex Diagnostics | US FDA | Available on request |
| Volumex 0.025 mCi/mL injectionIntravenous Cold chain | Iso-Tex Diagnostics | US FDA | Available on request |
Brands by market
2 brand names across 1 markets.
Manufacturers
Regulatory status
Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.
| Register | Status | Source |
|---|---|---|
| US FDA | Not recorded | — |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Questions and answers
Is Human serum albumin i-131 available for export from India?
Yes, on request. MedsAcross lists 2 presentations of Human serum albumin i-131 and sources them for licensed hospitals, importers and physicians against valid import documents.
What brand names does Human serum albumin i-131 have?
The catalogue lists 2 brand names for Human serum albumin i-131, including Megatope, Volumex.
Does Human serum albumin i-131 need cold chain shipping?
At least one listed presentation of Human serum albumin i-131 must be kept cold, so it is shipped in temperature-controlled packaging. Check the storage line on each presentation.
References
- Megatope prescribing information (Iso-Tex Diagnostics). U.S. National Library of Medicine, DailyMed. Retrieved 1 September 2023
Request Human serum albumin i-131 for export supply
Tell us the strength, quantity and destination country. Our team replies with availability, lead time and the import documents needed.