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Molecule

Levamlodipine

Also known as levamlodipine maleate
Available on request
Presentations
1
Brands
1
Manufacturers
1
Available from stock
0

Levamlodipine is a prescription medicine indicated for the treatment of hypertension in adults and patients 6 years and older, to lower blood pressure. It is available as tablets for oral use. MedsAcross supplies Levamlodipine for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.

Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review

Key facts

US FDA first approval
19 December 2019
EU status
Not recorded
Orphan designation
Not recorded
WHO essential medicine
Not recorded
India (CDSCO)
Not yet confirmed against CDSCO approval lists
Routes
Oral
Dosage forms
Tablet
Identifiers
UNII 0P6NLP6806CAS 103129-82-4DrugBank DB09237Q6534831

Clinical information

From the regulator-approved product information. Each section names its source.

Uses

CONJUPRI ® is calcium channel blocker and may be used alone or in combination with other antihypertensive and antianginal agents for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

Source: US FDA prescribing information

How it works

Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Experimental data suggest that amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Negative inotropic effects can be detected in vitro but such effects have not been seen in intact animals at therapeutic doses. Serum calcium concentration is not affected by amlodipine.

Source: US FDA prescribing information

Dosing overview

• Adult recommended starting dose: 2.5 mg once daily with maximum dose 5 mg once daily. ○ Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 1.25 mg once daily. • Pediatric starting dose: 1.25 mg to 2.5 mg once daily. Important Limitation: Doses in excess of 2.5 mg daily have not been studied in pediatric patients.

Source: US FDA prescribing information

Contraindications

Levamlodipine is contraindicated in patients with known sensitivity to amlodipine. Known sensitivity to amlodipine.

Source: US FDA prescribing information

Warnings and precautions

Symptomatic hypotension is possible, particularly in patients with severe aortic stenosis. However, acute hypotension is unlikely. Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of amlodipine, particularly in patients with severe obstructive coronary artery disease. Titrate slowly in patients with severe hepatic impairment.

Source: US FDA prescribing information

Side effects

Most common adverse reactions to amlodipine is edema which occurred in a dose related manner. Other adverse experiences not dose related but reported with an incidence >1.0% are fatigue, nausea, abdominal pain and somnolence.

Source: US FDA prescribing information

Interactions

Do not exceed doses greater than 20 mg daily of simvastatin. Impact of Other Drugs on Amlodipine CYP3A Inhibitors Co-administration with CYP3A inhibitors (moderate and strong) results in increased systemic exposure to amlodipine and may require dose reduction. Monitor for symptoms of hypotension and edema when amlodipine is co-administered with CYP3A inhibitors to determine the need for dose adjustment CYP3A Inducers No information is available on the quantitative effects of CYP3A inducers on amlodipine. Blood pressure should be closely monitored when amlodipine is co-administered with CYP3A inducers. Sildenafil Monitor for hypotension when sildenafil is co-administered with amlodipine.

Source: US FDA prescribing information

Storage

Storage Store bottles at 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F).

Source: US FDA prescribing information

For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.

All presentations

1 presentations of Levamlodipine, sorted by availability.

MedicineManufacturerRegisterAvailability
Conjupri 2.5 mg/2.5 mg tabletOralCSPC Ouyi PharmaceuticalUS FDAAvailable on request

Brands by market

1 brand names across 1 markets.

Brand names by country

United States

Manufacturers

Regulatory status

Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.

RegisterStatusSource
US FDAFirst approved 19 December 2019Drugs@FDA
EU (EMA)Not recorded—
India (CDSCO)Not yet confirmed against CDSCO approval lists—
United StatesRegisteredUS FDA (NDC directory, openFDA)Checked 12 November 2026

Questions and answers

Is Levamlodipine available for export from India?

Yes, on request. MedsAcross lists 1 presentations of Levamlodipine and sources them for licensed hospitals, importers and physicians against valid import documents.

What brand names does Levamlodipine have?

The catalogue lists 1 brand names for Levamlodipine, including Conjupri.

Is Levamlodipine approved by the US FDA?

Yes. The US FDA first approved Levamlodipine on 19 December 2019, according to Drugs@FDA.

Does Levamlodipine need cold chain shipping?

No listed presentation of Levamlodipine is recorded as needing a cold chain. Storage conditions are shown on each presentation page.

References

  1. Conjupri prescribing information (CSPC Ouyi Pharmaceutical). U.S. National Library of Medicine, DailyMed. Retrieved 11 December 2024

Request Levamlodipine for export supply

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