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MedsAcross

Molecule

Tapinarof

Aryl Hydrocarbon Receptor Agonist
Available on request
Presentations
1
Brands
1
Manufacturers
1
Available from stock
0

Tapinarof is an aryl hydrocarbon receptor agonist indicated for the topical treatment of plaque psoriasis in adults, among other approved uses. It is available as cream for topical use. MedsAcross supplies Tapinarof for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.

Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review

Key facts

Pharmacological class
Aryl Hydrocarbon Receptor Agonist, Aryl Hydrocarbon Receptor Agonists
US FDA first approval
23 May 2022
EU status
Not recorded
Orphan designation
Not recorded
WHO essential medicine
Not recorded
India (CDSCO)
Not yet confirmed against CDSCO approval lists
Routes
Topical
Dosage forms
Cream
Identifiers
UNII 84HW7D0V04CAS 79338-84-4DrugBank DB06083Q76386711

Clinical information

From the regulator-approved product information. Each section names its source.

Uses

VTAMA cream, 1% is an aryl hydrocarbon receptor agonist indicated for: the topical treatment of plaque psoriasis in adults. the topical treatment of atopic dermatitis in adults and pediatric patients 2 years of age and older.

Source: US FDA prescribing information

How it works

Tapinarof is an aryl hydrocarbon receptor (AhR) agonist. The specific mechanisms by which VTAMA cream exerts its therapeutic actions are unknown.

Source: US FDA prescribing information

Dosing overview

Apply a thin layer of VTAMA cream to affected areas once daily. Wash hands after application, unless VTAMA cream is for treatment of the hands. VTAMA cream is not for oral, ophthalmic, or intravaginal use.

Source: US FDA prescribing information

Side effects

In plaque psoriasis, the most common adverse reactions (incidence ≥ 1%) were folliculitis, nasopharyngitis, contact dermatitis, headache, pruritus, and influenza. In atopic dermatitis, the most common adverse reactions (incidence ≥ 1%) were upper respiratory tract infection, folliculitis, lower respiratory tract infection, headache, asthma, vomiting, ear infection, pain in extremity, and abdominal pain.

Source: US FDA prescribing information

Storage

- Store at 20°C to 25°C (68°F to 77°F) excursions permitted between 15°C and 30°C (59°F and 86°F). - Do not freeze. - Protect from exposure to excessive heat.

Source: US FDA prescribing information

For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.

All presentations

1 presentations of Tapinarof, sorted by availability.

MedicineManufacturerRegisterAvailability
Vtama 1% creamTopicalOrganonUS FDAAvailable on request

Brands by market

1 brand names across 1 markets.

Brand names by country

United States

Manufacturers

Regulatory status

Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.

RegisterStatusSource
US FDAFirst approved 23 May 2022Drugs@FDA
EU (EMA)Not recorded—
India (CDSCO)Not yet confirmed against CDSCO approval lists—
United StatesRegisteredUS FDA (NDC directory, openFDA)Checked 12 November 2026

Questions and answers

Is Tapinarof available for export from India?

Yes, on request. MedsAcross lists 1 presentations of Tapinarof and sources them for licensed hospitals, importers and physicians against valid import documents.

What brand names does Tapinarof have?

The catalogue lists 1 brand names for Tapinarof, including Vtama.

Is Tapinarof approved by the US FDA?

Yes. The US FDA first approved Tapinarof on 23 May 2022, according to Drugs@FDA.

Does Tapinarof need cold chain shipping?

No listed presentation of Tapinarof is recorded as needing a cold chain. Storage conditions are shown on each presentation page.

References

  1. VTAMA prescribing information (Organon). U.S. National Library of Medicine, DailyMed. Retrieved 28 May 2025

Request Tapinarof for export supply

Tell us the strength, quantity and destination country. Our team replies with availability, lead time and the import documents needed.