Uses
SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP is intended for use only for the anticoagulation of whole blood as part of automated apheresis procedures.
Source: US FDA prescribing information
Molecule
Trisodium
Also known as trisodium citrate dihydrate
Available on request
- Presentations
- 7
- Brands
- 5
- Manufacturers
- 5
- Available from stock
- 0
Trisodium is an anti-coagulant. It is available as injection and solution for intravenous and extracorporeal use. MedsAcross supplies Trisodium for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
Key facts
- Pharmacological class
- Anti-coagulant, Calculi Dissolution Agent, Acidifying Activity, Calcium Chelating Activity, Decreased Coagulation Factor Activity
- US FDA first approval
- Not recorded
- EU status
- Not recorded
- Orphan designation
- Not recorded
- WHO essential medicine
- Not recorded
- India (CDSCO)
- Not yet confirmed against CDSCO approval lists
- Routes
- Intravenous, Extracorporeal
- Dosage forms
- Injection, Solution
- Identifiers
- UNII B22547B95KRxCUI 221163CAS 6132-04-3DrugBank DB09159Q22075862
Clinical information
From the regulator-approved product information. Each section names its source.
How it works
SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP acts as an extracorporeal anticoagulant by binding the free calcium in the blood. Calcium is a necessary co-factor to several steps in the clotting cascade. The following ingredients are key components of the solution: Citric acid for pH regulation Sodium Citrate anticoagulant This solution has no pharmacological effect.
Source: US FDA prescribing information
Dosing overview
SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP is added to tubing sets during apheresis procedures. SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP may only be used with apheresis devices. For instructions on the use of the solution see the apheresis device operator's manual. Follow the directions for connecting the SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP bag to the apheresis system.
Source: US FDA prescribing information
Contraindications
DO NOT INFUSE SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP DIRECTLY TO THE DONOR.
Source: US FDA prescribing information
Warnings and precautions
Verify that the SODIUM CITRATE 4% W/V ANTICOAGULANT SOLUTION USP has been securely attached to the anticoagulant (AC) line on the system tubing set. Use aseptic technique throughout all procedures to ensure donor safety and quality. Single-use container. Do not reuse. Discard any unused or partially used product. Rx only. Single-use container, do not reuse. Rx only
Source: US FDA prescribing information
Side effects
Citrate reactions or toxicity may occur with the infusion of blood products to patients and return of blood containing citrate anticoagulant to donors. The recipient of the blood containing citrate should be monitored for the signs and symptoms of citrate toxicity. The signs and symptoms of citrate toxicity begin with paresthesia, a "tingling" sensation around the mouth or in the extremities, followed by severe reactions that are characterized by hypotension and possible cardiac arrhythmia. Citrate toxicity may occur more frequently in patients who are hypothermic, have impaired liver or renal function, or have low calcium levels because of an underlying disease. Citrate reactions or toxicity may occur with the infusion and return of blood containing citrate anticoagulant.
Source: US FDA prescribing information
Storage
Up to 25 °C. Protect from freezing.
Source: US FDA prescribing information
For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
All presentations
7 presentations of Trisodium, sorted by availability.
| Medicine | Manufacturer | Register | Availability |
|---|---|---|---|
| Anticoagulant Sodium Citrate 40 mg/mL solutionExtracorporeal | Laboratorios Grifols | US FDA | Available on request |
| Sodium Citrate Blood-Pack Units, (PL 146 Plastic) 10 g/250 mL injectionIntravenous | Fenwal | US FDA | Available on request |
| triCitrasol 14 g/30 mL solutionExtracorporeal | Citra Labs | US FDA | Available on request |
| Anticoagulant Sodium Citrate 40 mg/mL solutionExtracorporeal | Baxter Healthcare | US FDA | Available on request |
| Sodium Citrate 4% w/v Anticoagulant 10 g/250 mL injectionIntravenous | Terumo BCT | US FDA | Available on request |
| Sodium Citrate Blood-Pack Units, (PL 146 Plastic) 20 g/500 mL injectionIntravenous | Fenwal | US FDA | Available on request |
| Sodium Citrate w/v Anticoagulant 10 g/250 mL injectionIntravenous | Terumo BCT | US FDA | Available on request |
Brands by market
5 brand names across 1 markets.
Manufacturers
Regulatory status
Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.
| Register | Status | Source |
|---|---|---|
| US FDA | Not recorded | — |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Questions and answers
Is Trisodium available for export from India?
Yes, on request. MedsAcross lists 7 presentations of Trisodium and sources them for licensed hospitals, importers and physicians against valid import documents.
What brand names does Trisodium have?
The catalogue lists 5 brand names for Trisodium, including Anticoagulant Sodium Citrate, Sodium Citrate 4% w/v Anticoagulant, Sodium Citrate Blood-Pack Units, (PL 146 Plastic), Sodium Citrate w/v Anticoagulant, triCitrasol.
Does Trisodium need cold chain shipping?
No listed presentation of Trisodium is recorded as needing a cold chain. Storage conditions are shown on each presentation page.
References
- Sodium Citrate w/v Anticoagulant prescribing information (Terumo BCT). U.S. National Library of Medicine, DailyMed. Retrieved 24 January 2025
Request Trisodium for export supply
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