Uses
Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.
Source: US FDA prescribing information
- Presentations
- 3
- Brands
- 0
- Manufacturers
- 0
- Available from stock
- 0
Vasopressin is a prescription medicine indicated to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. It is available as injection for intravenous use. MedsAcross supplies Vasopressin for export from India to licensed hospitals, importers and physicians acting for named patients, with the documents each country requires.
Information from the US FDA prescribing information, retrieved 12 November 2026. Not yet medically reviewed.How we review
Key facts
- Pharmacological class
- Decreased Diuresis, Vasoconstriction
- ATC classification
- H01BA01 Vasopressin · Vasopressin receptor agonist
- US FDA first approval
- 17 April 2014
- EU status
- Not recorded
- Orphan designation
- Not recorded
- WHO essential medicine
- Not recorded
- India (CDSCO)
- Not yet confirmed against CDSCO approval lists
- Routes
- Intravenous
- Dosage forms
- Injection
- Identifiers
- UNII Y4907O6MFDRxCUI 11149CAS 113-79-1Q183011
Clinical information
From the regulator-approved product information. Each section names its source.
How it works
Vasopressin causes vasoconstriction by binding to V 1 receptors on vascular smooth muscle coupled to the Gq/11-phospholipase C-phosphatidyl-inositol-triphosphate pathway, resulting in the release of intracellular calcium. In addition, vasopressin stimulates antidiuresis via stimulation of V 2 receptors which are coupled to adenyl cyclase.
Source: US FDA prescribing information
Dosing overview
Dilute vasopressin injection with 0.9% Sodium Chloride Injection or 5% Dextrose Injection to either 0.1 units/mL or 1 unit/mL for intravenous administration. Discard unused diluted solution after 18 hours at room temperature or 24 hours under refrigeration. Post-cardiotomy shock: 0.03 units/minute to 0.1 units/minute. Septic shock: 0.01 units/minute to 0.07 units/minute.
Source: US FDA prescribing information
Contraindications
Vasopressin injection 1 mL single-dose vial and 10 mL multiple-dose vial are contraindicated in patients with known allergy or hypersensitivity to 8-L-arginine vasopressin or chlorobutanol.
Source: US FDA prescribing information
Warnings and precautions
Can worsen cardiac function. Reversible diabetes insipidus Worsening Cardiac Function A decrease in cardiac index may be observed with use of vasopressin.
Source: US FDA prescribing information
Side effects
The following adverse reactions associated with the use of vasopressin were identified in the literature. Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to estimate their frequency reliably or to establish a causal relationship to drug exposure. Bleeding/lymphatic system disorders: Hemorrhagic shock, decreased platelets, intractable bleeding Cardiac disorders: Right heart failure, atrial fibrillation, bradycardia, myocardial ischemia Gastrointestinal disorders: Mesenteric ischemia Hepatobiliary: Increased bilirubin levels Renal/urinary disorders: Acute renal insufficiency Vascular disorders: Distal limb ischemia Metabolic: Hyponatremia Skin: Ischemic lesions Postmarketing Experience Reversible diabetes insipidus.
Source: US FDA prescribing information
Interactions
Pressor effects of catecholamines and vasopressin injection are expected to be additive. Indomethacin may prolong effects of vasopressin injection. Co-administration of ganglionic blockers or drugs causing SIADH (syndrome of inappropriate antidiuretic hormone secretion) may increase the pressor response. Co-administration of drugs causing diabetes insipidus may decrease the pressor response.
Source: US FDA prescribing information
Storage
Storage is permitted for up to 12 months at controlled room temperature (USP) 20°C to 25°C (68°F to 77°F) within the expiry date. Once removed from refrigeration, mark the unopened vial with the revised 12-month expiration date. Do not return Vasopressin to the refrigerator after it has been stored at room temperature. Discard the product after 12 months at room temperature or at the expiry date, whichever is earlier. Store refrigerated between 2°C and 8°C (36°F and 46°F). Do not freeze.
Source: US FDA prescribing information
For healthcare professionals and buyers. This is not medical advice. Treatment decisions belong to the prescriber.
All presentations
3 presentations of Vasopressin, sorted by availability.
| Medicine | Manufacturer | Register | Availability |
|---|---|---|---|
| Vasopressin 20 units/mL injectionIntravenous Cold chainGeneric name | — | US FDA | Available on request |
| Vasopressin 0.4 units/mL injectionIntravenous Cold chainGeneric name | — | US FDA | Available on request |
| Vasopressin 0.2 units/mL injectionIntravenous Cold chainGeneric name | — | US FDA | Available on request |
Regulatory status
Approval facts from US FDA, EMA and CDSCO data, and registration status by country where we hold register data.
| Register | Status | Source |
|---|---|---|
| US FDA | First approved 17 April 2014 | Drugs@FDA |
| EU (EMA) | Not recorded | — |
| India (CDSCO) | Not yet confirmed against CDSCO approval lists | — |
| United States | Registered | US FDA (NDC directory, openFDA)Checked 12 November 2026 |
Conditions
Conditions linked to Vasopressin in public data. This is not a list of approved uses, see the clinical information.
Questions and answers
Is Vasopressin available for export from India?
Yes, on request. MedsAcross lists 3 presentations of Vasopressin and sources them for licensed hospitals, importers and physicians against valid import documents.
Is Vasopressin approved by the US FDA?
Yes. The US FDA first approved Vasopressin on 17 April 2014, according to Drugs@FDA.
Does Vasopressin need cold chain shipping?
At least one listed presentation of Vasopressin must be kept cold, so it is shipped in temperature-controlled packaging. Check the storage line on each presentation.
Which ATC class is Vasopressin in?
Vasopressin is classified under ATC code H01BA01 (Vasopressin).
References
- Vasopressin prescribing information (Civica). U.S. National Library of Medicine, DailyMed. Retrieved 1 March 2025
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